B.R.L Laboratory Inc. is research – based biotechnology company committed to deliver truly innovative and life-changing treatments and technologies for our customers worldwide. At B.R.L we discover, develop, manufacture and deliver unique solutions for human and pet care in areas of unmet health need, specializing in technologies to treat immune system problems and addressing the issues of aging and increasing longevity in humans and animals.

Investing heavily in research and development and taking unique perspective, B.R.L has been able to offer customers options that can enhance their quality of life and is developing a pipeline of medicines and supplements with breakaway potential.

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Liposomes

Liposomes Properties

liposomes
  • LIPOSOMES CAN SIMULTANEOUSLY ENCAPSULATE HYDROPHILIC (A) AND HYDRORHOBIC (B) ACTIVE INGREDIENTS IN ONE PRODUCT;
  • HIGH TRANSLAMINAR ACTIVITY OF LIPOSOMES INCREASE EFFICIENCY OF ACTIVE INGREDIENTS;
  • PHOSPHOLIPIDS (BASE OF LIPOSOMES) RESTORE DAMAGED CELLS;
  • PHOSPHOLIPIDS ARE OBTAINED FROM NATURAL SOURCES;
  • THE USE OF LIPOSOMES DO NOT RESULT IN ALLERGIC REACTIONS;
liposomes


Liposome Structure

liposomes
phospholipid molecule - phospholipid molecule
PHOSPHOLIPID COMPOSITION:
PHOSPHATIDYL CHOLINE
PHOSPHATIDYL ETHANOLAMINE
PHOSPHATIDYL INOSITOL
NONPOLAR LIPIDS
LYSOPHOSPHATIDYL CHOLINE
FREE FATTY ACIDS 		68 – 94 %
0,1 – 10 %
n.m.t. 0,1 %
2 – 6 %
3 – 5 %
n.m.t. 0,5 %
FATTY ACID COMPOSITION:
PALMITIC ACID
STEARIC ACID
OLEIC ACID
LINOLEIC ACID
LINOLENIC ACID 		12 – 20 %
2 – 5 %
8 – 15 %
58 – 70 %
3 – 7 %
liposomes

MLVs: 100 - 1000 nm
SIZE RANGE: 40 – 1000 nm
PEROXIDE VALUE [meg O2/kg]: n.m.t. 3


Liposome Advantages

  • High productivity: up to 40 l/h;
  • Controlled liposome size in the range 40 – 1000 NM with high reproducibility;
  • Controlled content of phospholipids in the range 1 – 35 g/l;
  • Soft conditions of the liposomes formation (no high pressure and temperature) expand a range of products (liposomal products with antibodies, enzymes, bioactive proteins and others);
  • High encapsulation efficiency in the range 40 – 60% for hydrophilic and 90 – 100% for hydrophobic substances;
  • Equipment is characterized by portability, power efficiency, ecological compatibility, simplicity in use.

Liposome Assortment

We can produce liposomal products with a wide range of encapsulated bioactive substances in different compositions.


VITAMINS

Vitamins

PROTEINS

Proteins

PHARMACEUTICAL AND VETERINARY SUBSTANCES

Pharmaceutical and veterinary substances

HERBAL EXTRACTS AND ESSENTIAL OILS

Herbal extracts and essential oils